The data points were obtained at baseline, day one, and day three of MV. A total of 85 patients with ARDS on invasive MV were included. The primary outcome was survival at the end of intensive care unit (ICU) stay. They were at baseline, i.e., after intubation and initiation of MV (within one hour of intubation), day one (1–24 hours of MV), and day three (48–72 hours of MV). The values of PaO 2, FiO 2, and SpO 2 were collected at three different time points. Patients aged 18–80 years on invasive mechanical ventilation (MV) diagnosed with ARDS as defined by the Berlin definition were included. The secondary objective was to determine the cut-off value of S/FP 10 ratio to predict severe ARDS and survival. The primary objective was to determine the correlation of S/FP 10 to P/FP 10 ratio in ARDS patients. To evaluate if pulse oximetry is a reliable indicator of oxygenation in ARDS patients by calculating SpO 2 10/FiO 2 PEEP (S/FP 10). The aim of this study was to correlate SpO 2 10/FiO 2 PEEP (S/FP 10) to PaO 2 10/FiO 2 PEEP (P/FP 10) and evaluate the utility of S/FP 10 as a reliable noninvasive indicator of oxygenation in ARDS to avoid repeated arterial blood sampling. Recent literature has shown that incorporation of positive end-expiratory pressure (PEEP) into the P/F ratio (PaO 2 10/FiO 2 PEEP or P/FP 10) has a much better prognostic ability in ARDS as compared to P/F ratio. Conventionally, PaO 2/FiO 2 (P/F ratio) has been used to categorize severity of acute respiratory distress syndrome (ARDS) and prognostication of outcome. There was no effect of convalescent plasma in ICU mortality and no improvement was observed in terms of oxygen support requirements. The length of stay of patients in the convalescent plasma group was significantly longer than the control group. Deceased patients, who received convalescent plasma, stayed longer in the ICU with a mean length of stay of 12.87 ± 5.7 days versus 8.13 ± 4.8 days with a significant difference ( U = 434 ). ICU LoS was longer in patients, who had prior history of hypertension (aOR = 2.14 95% CI (1.05, 4.35) ) and received convalescent plasma (aOR = 3.88 95% CI (1.77, 8.05) ). Less patients that received convalescent plasma presented with the need for mechanical ventilation on ICU admission, but with comparable PaO 2 to FiO 2 (P/F) ratio. Overall mortality rate in our COVID-19 ICU was 55.3%, with a median overall length of stay of 8 (4–11) days. Data were analyzed using multiple logistic regression to make prediction models of mortality, length of stay, and oxygen support device requirement. We dichotomized the variables and compared outcome data of 48 patients, who received convalescent plasma to 131 patients, receiving standard of care. Data of all severe and critically-ill patients in our COVID-19 ICU was collected retrospectively between May and November 2020. This study aims to investigate its effects on ICU mortality, ICU length of stay (LoS), and improvement of oxygen support requirements. Convalescent plasma administration in severe and critically-ill COVID-19 patients have been proven to not provide improvement in patients’ outcome, yet it is still widely used in countries with limited resources due to its high availability and safety.
XML Documents Validation and Content Completion Based on XML Schema 1.Bambang Pujo Semedi | Nadya Noor Ramadhania |.Select or Search to Insert Cross References in DocBook Documents.Refactoring Action to Move or Rename DITA Topics.
Support for Configuring Specific Background and Foreground Tag Colors for Any XML Element.Support for Specifying Widths to Inline Elements.Edit Profiling Attributes Using Form Controls.Trigger Actions Directly from the Author View.Edit Attributes Directly in the Author View.This also expands the range of documents that can be edited visually to any XML document, no matter where the content is stored, in elements or attributes. Version 14.1 of oXygen XML Author makes the XML authoring available to everybody, by allowing attributes to be edited directly in the Author view though form-like controls and placing actions directly in the document flow.
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